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typhoid fever
Columbia Encyclopedia entry: typhoid fever
Typhoid fever acute, generalized infection caused by Salmonella typhi. The main sources of infection are contaminated water or milk and, especially in urban communities, food handlers who are carriers. The symptoms of typhoid appear 10 to 14 days after infection; they include high fever, rose-colored spots on the abdomen and chest, diarrhea or constipation, and enlargement of the spleen. Complications, especially in untreated patients, may be numerous, affecting practically every body system, and they account for the mortality rate of 7% to 14%. Perforation of the intestine with hemorrhage is not uncommon. Chloramphenicol is the most effective drug in combating typhoid, and in very toxic patients a cortisone derivative may be helpful. Skilled nursing care is still of the utmost importance, as is a high caloric diet to prevent wasting of the body. Vaccination against typhoid is a valuable preventive measure, especially for persons in military service and for those who travel to poorly sanitized regions.
Wikipedia search results for: Typhoid fever
From Wikipedia, the free encyclopedia
Typhoid fever, also known as Salmonella Typhi or commonly just typhoid, is an illness. Common worldwide, it is transmitted by the ingestion of food or water contaminated with feces from an infected person. The bacteria then perforate through the intestinal wall and are phagocytosed by macrophages. Salmonella Typhi, more correctly called Salmonella enterica enterica Typhi, then alters its structure to resist destruction and allow them to exist within the macrophage. This renders them resistant to damage by PMN's, complement and the immune response. The organism is then spread via the lymphatics while inside the...more »
Columbia Encyclopedia search results: typhoid fever
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  • salmonellosis

    Salmonellosis, any of a group of infectious diseases caused by intestinal bacteria of the genus Salmonella, including typhoid fever, paratyphoid fever, blood poisoning, and food poisoning (gas...

  • Bretonneau, Pierre

    Bretonneau, Pierre, 1778–1862, French physician. He performed (1825) the first successful tracheotomy for laryngeal diphtheria, wrote a treatise (1826) distinguishing between scarlet fever and...

  • housefly

    Housefly, common name of the fly Musca domestica, found in most parts of the world. The housefly, a scavenger, does not bite living animals but is dangerous because it carries bacteria and pro...

  • hemorrhage

    Hemorrhage, escape of blood from the circulation (arteries, veins, capillaries) to the internal or external tissues. The term is usually applied to a loss of blood that is copious enough to th...

  • chloramphenicol

    Chloramphenicol, antibiotic effective against a wide range of gram-negative and gram-positive bacteria (see Gram's stain). It was originally isolated from a species of Streptomyces bacteria. C...

  • baldness

    Baldness, thinning or loss of hair as a result of illness, functional disorder, or hereditary disposition; also known as alopecia. Male pattern baldness, a genetic trait, is the most common ca...

  • diarrhea

    Diarrhea, frequent discharge of watery feces from the intestines, sometimes containing blood and mucus. It can be caused by excessive indulgence in alcohol or other liquids or foods that prove...

  • parasite

    Parasite, plant or animal that at some stage of its existence obtains its nourishment from another living organism called the host. Parasites may or may not harm the host, but they never benef...

  • vaccination

    Vaccination, means of producing immunity against pathogens, such as viruses and bacteria, by the introduction of live, killed, or altered antigens that stimulate the body to produce antibodies...

  • Douglas, Stephen Arnold

    Douglas, Stephen Arnold, 1813–61, American statesman, b. Brandon, Vt. He was admitted to the bar at Jacksonville, Ill., in 1834. After holding various state and local offices he became a U.S. ...

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