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thyroid gland
Columbia Encyclopedia entry: thyroid gland
Thyroid gland, endocrine gland, situated in the neck, that secretes hormones necessary for growth and proper metabolism. It consists of two lobes connected by a narrow segment called the isthmus. The lobes lie on either side of the trachea, the isthmus in front of it. Thyroid tissue is composed of millions of tiny saclike follicles, which store thyroid hormone in the form of thyroglobulin, a glycoprotein. Blood capillaries attached to the gland yield a constant supply of plasma. The protein thyroglobulin is the chief component of the jellylike substance, called colloid, that is secreted by the follicles. It attaches to the thyroid hormone for storage purposes; when the hormone is ready to be released, the protein detaches itself. Before it is released into the bloodstream, the thyroid hormone is converted into thyroxine and small quantities of the other closely related thyroid hormones. The amount of thyroxine production (and therefore the metabolic rate) is dependent on a sufficient intake of iodine and on stimulation by thyroid-stimulating hormone (TSH) from the pituitary gland. Metabolic disorders result when the thyroid secretes too little or too much thyroxine. Deficiencies in thyroid secretion (hypothyroidism) occur when there is insufficient iodine in the diet. A disease known as goiter results from the deficiency, although it has been virtually eliminated by the use of iodized salt. Hypothyroidism that results from glandular malfunction is known as myxedema in the adult and cretinism in infancy and childhood. Treatment is by administration of thyroxine. Excessive secretion of thyroxine, or hyperthyroidism, causes an increased metabolic rate, loss of weight despite good appetite, protrusion of the eyeballs, rapid pulse, and irritability. The condition, also known as Graves' disease, may be accompanied by enlargement of the thyroid. The thyroid gland also produces the hormone calcitonin, which is involved in the regulation of serum calcium in the body. See also endocrine system.
Wikipedia search results for: Thyroid
From Wikipedia, the free encyclopedia
In vertebrate anatomy, the thyroid gland (redirected from thyroid gland) or simply, the thyroid, is one of the largest endocrine glands in the body, and is not to be confused with the "parathyroid glands". The thyroid gland is found in the neck, inferior to the thyroid cartilage and at approximately the same level as the cricoid cartilage. The thyroid controls how quickly the body uses energy, makes proteins, and controls how sensitive the body should be to other hormones. The thyroid gland participates in these processes by producing thyroid hormones, principally triiodothyronine and thyroxine. These hormones regulate the rate of metabolism and affect the growth and rate of...more »
Columbia Encyclopedia search results: thyroid gland
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  • gland

    Gland, organ that manufactures chemical substances. A gland may vary from a single cell to a complex system of tubes that unite and open onto a surface through a duct. The endocrine glands, e....

  • parathyroid glands

    Parathyroid glands, four small endocrine bodies, located behind the thyroid gland, that govern calcium and phosphorus metabolism. These four masses of tissue (each about the size of a pea) are...

  • pituitary gland

    Pituitary gland, small oval endocrine gland that lies at the base of the brain. It is sometimes called the master gland of the body because all the other endocrine glands depend on its secreti...

  • endocrine system

    Endocrine system, body control system composed of a group of glands that maintain a stable internal environment by producing chemical regulatory substances called hormones. The endocrine syste...

  • thyroxine

    Thyroxine, substance secreted by the thyroid gland. The hormone thyroxine forms by combining the amino acid tyrosine with iodine. Complexed to a protein, it is stored in the follicle stems bet...

  • thyrotropin

    Thyrotropin or thyroid-stimulating hormone (TSH), hormone released by the anterior pituitary gland that stimulates the thyroid gland to release thyroxine. The release of thyrotropin is trigger...

  • neoteny

    Neoteny, in biology, sexual maturity reached in the larval stage of some animals. Certain environmental conditions can inhibit the completion of metamorphosis; low temperature or lack of avail...

  • Kendall, Edward Calvin

    Kendall, Edward Calvin, 1886–1972, American biochemist, b. South Norwalk, Conn., grad. Columbia (B.S., 1908; Ph.D., 1910). At St. Luke's Hospital, New York City, he did research on the thyroid...

  • molting

    Molting, periodical shedding and renewal of the outer skin, exoskeleton, fur, or feathers of an animal. In most animals the process is triggered by secretions of the thyroid and pituitary glan...

  • cretinism

    Cretinism, condition produced in infants and children due to lack of thyroid hormone. It usually results from a congenital defect (e.g., absence of the thyroid, presence of only a rudimentary ...

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