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genetic engineering
Columbia Encyclopedia entry: genetic engineering
Genetic engineering, the use of various methods to manipulate the DNA (genetic material) of cells to change hereditary traits or produce biological products. The techniques include the use of hybridomas (hybrids of rapidly multiplying cancer cells and of cells that make a desired antibody) to make monoclonal antibodies; gene splicing or recombinant DNA, in which the DNA of a desired gene is inserted into the DNA of a bacterium, which then reproduces itself, yielding more of the desired gene; and polymerase chain reaction, which makes perfect copies of DNA fragments and is used in DNA fingerprinting.

Genetically engineered products include bacteria designed to break down oil slicks and industrial waste products, drugs (human and bovine growth hormones, human insulin, interferon), and plants that are resistant to diseases, insects, and herbicides, that yield fruits or vegetables with desired qualities, or that produce toxins that act as pesticides. Genetic engineering techniques have also been used in the direct genetic alteration of livestock and laboratory animals (see pharming). Genetically engineered products usually require the approval of at least one U.S. government agency, such as the Dept. of Agriculture, the Food and Drug Administration, or the Environmental Protection Agency.

Because genetic engineering involves techniques used to obtain patents on human genes and to create patentable living organisms, it has raised many legal and ethical issues. The safety of releasing into the environment genetically altered organisms that might disrupt ecosystems has also been questioned. The discovery in 2001 of genetically engineered DNA in native Mexican corn varieties made concerns of genetic pollution actual, and led some scientists to worry that the spread of transgenes through cross-pollination could lead to a reduction in genetic diversity in important crops. Imports of genetically modified corn, soybeans, and other crops have been curtailed or limited in some countries, and the vast majority of such crops are grown in just a handful of nations. The Cartagena Protocol on Biosafety, which has been signed by more than 100 nations and took effect in Sept., 2003, requires detailed information on whether and how imported seeds, plants, animals, other organisms, and the like are genetically modified and permits a nation to bar those imports, but a 2006 World Trade Organization decision treated the banning of genetically modified crops as a form of protectionism. The United States is not party to the 2003 treaty.

Wikipedia search results for: Genetic engineering
From Wikipedia, the free encyclopedia
Genetic engineering, recombinant DNA technology, genetic modification/manipulation and gene splicing are terms that apply to the direct manipulation of an organism's genes. Genetic engineering is different from traditional breeding, where the organism's genes are manipulated indirectly. Genetic engineering uses the techniques of molecular cloning and transformation to alter the structure and characteristics of genes directly. Genetic engineering techniques have found some successes in numerous applications. Some examples are in improving crop technology, the manufacture of synthetic human insulin through the use of modified...more »
Columbia Encyclopedia search results: genetic engineering
Results 1 - 10  of 36
  • genetics

    Genetics, scientific study of the mechanism of heredity. While Gregor Mendel first presented his findings on the statistical laws governing the transmission of certain traits from generation t...

  • engineering

    Engineering, profession devoted to designing, constructing, and operating the structures, machines, and other devices of industry and everyday life. The primary types of engineering are chemic...

  • gene therapy

    Gene therapy, the use of genes and the techniques of genetic engineering in the treatment of a genetic disorder or chronic disease. There are many techniques of gene therapy, all of them still...

  • insulin

    Insulin, hormone secreted by the ß cells of the islets of Langerhans, specific groups of cells in the pancreas. Insufficiency of insulin in the body results in diabetes. Insulin was one of the...

  • New Mexico State University

    New Mexico State University, at Las Cruces; land-grant and state supported; coeducational; chartered and opened 1889 as a college. It became New Mexico State Univ. of Engineering, Agriculture,...

  • plant breeding

    Plant breeding, science of altering the genetic pattern of plants in order to increase their value. Increased crop yield is the primary aim of most plant-breeding programs; advantages of the h...

  • pharming

    Pharming, the use of genetically altered livestock, such as cows, goats, pigs, and chickens, to produce medically useful products. In pharming, researchers first create hybrid genes using anim...

  • blood substitute

    Blood substitute, substance that mimics the function of blood. Blood substitutes typically concentrate only on reproducing the function of hemoglobin, the molecule that carries oxygen through ...

  • uremia

    Uremia, condition resulting from advanced stages of kidney failure in which urea and other nitrogen-containing wastes are found in the blood. Uremia can be caused by NSAIDs (nonsteroid anti-in...

  • biotechnology

    Biotechnology, the use of biological processes, as through the exploitation and manipulation of living organisms or biological systems, in the development or manufacture of a product or in the...

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