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Addisons disease
Columbia Encyclopedia entry: Addison's disease
Addison's disease [for Thomas Addison], progressive disease brought about by atrophy of the outer layer, or cortex, of the adrenal gland; it is also called chronic adrenocortical insufficiency. The deterioration of this tissue causes a decrease in the secretion of steroid hormones, many of which are necessary for the maintenance of life. In many cases the cause of the wasting process is not known; in others the predominant cause is the formation and infiltration of tumors, inflammatory disease, or surgery. Symptoms are increasing weakness, abnormal pigmentation of the skin and mucous membranes, weight loss, low blood pressure, dehydration, and gastrointestinal upsets. Secondary Addison's disease is most commonly caused by acute withdrawal of steroids. Once considered inevitably fatal, Addison's disease can now be treated with injections of adrenocortical hormones.
Wikipedia search results for: Addison's disease
From Wikipedia, the free encyclopedia
Addison’s disease (redirected from Addisons disease) is a rare endocrine disorder wherein the adrenal glands produce insufficient steroid hormones ; and generally is diagnosed via blood tests and medical imaging. Its treatment involves replacing the absent hormones. Regular follow-up treatment and monitoring for other health problems is necessary. Addison’s disease is named after Dr Thomas Addison, the British physician who first described the condition in On the Constitutional and Local Effects of Disease of the Suprarenal Capsules. The adjective "Addisonian" describes features of the condition, and patients suffering Addison’s disease. While Addison's six patients in...more »
Columbia Encyclopedia search results: Addisons disease
Results 1 - 8  of 8
  • Addison, Thomas

    Addison, Thomas, 1793–1860, English physician, b. near Newcastle, grad. Univ. of Edinburgh (M.D., 1815). In 1837 he became a physician at Guy's Hospital, London, where he conducted important r...

  • hydrocortisone

    Hydrocortisone, another name for the steroid hormone cortisol, more especially used to refer to preparations of this hormone used medicinally. Hydrocortisone, introduced in 1952, is more poten...

  • Barton, Derek H. R.

    Barton, Derek H. R., 1918–98, British chemist, b. Gravesend, England, grad. Imperial College of Science and Technology (B.S. 1940, Ph.D. 1942, D.Sc. 1949). He was on the faculty of Imperial Co...

  • adrenal gland

    Adrenal gland or suprarenal gland, endocrine gland (see endocrine system) about 2 in. (5.1 cm) long situated atop each kidney. The outer yellowish layer (cortex) of the adrenal gland secretes ...

  • steroids

    Steroids, class of lipids having a particular molecular ring structure called the cyclopentanoperhydro-phenanthrene ring system. Steroids differ from one another in the structure of various si...

  • corticosteroid drug

    Corticosteroid drug, any one of several synthetic or naturally occurring substances with the general chemical structure of steroids. They are used therapeutically to mimic or augment the effec...

  • cortisone

    Cortisone, steroid hormone whose main physiological effect is on carbohydrate metabolism. It is synthesized from cholesterol in the outer layer, or cortex, of the adrenal gland under the stimu...

  • Pope, Alexander

    Pope, Alexander, 1688–1744, English poet. Although his literary reputation declined somewhat during the 19th cent., he is now recognized as the greatest poet of the 18th cent. and the greatest...

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Addisons disease

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